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If you are taking this drug for RLS, tell your physician if your signs and symptoms get worse, if they take place in the early morning or earlier than normal at night, or if you feel agitated signs and symptoms in your hands or arms.



Do not stop utilizing this medication suddenly, or you could have unpleasant withdrawal signs. Follow your doctor's guidelines about tapering your dosage.



Pramipexole immediate-release: Initial dosage: 0.125 mg by mouth three times a day with or xerophagy. Maintenance dosage: The dose must be titrated progressively to the preferred medical result. Typically, the dose could be increased every 5 to 7 days based on efficacy and tolerability, up to a maximum of 4.5 mg/day (offered as 1.5 mg 3 times a day). The efficacy of doses past 4.5 mg/day has actually not been developed. Pramipexole extended-release: Initial dosage: 0.375 mg once daily with or xerophagy. Upkeep dosage: The dosage must be titrated progressively to the desired professional result. Generally, the dose might be boosted every 5 to 7 days based upon efficacy and tolerability, initially to 0.75 milligrams daily then by 0.75 milligrams increments approximately a max suggested dosage of 4.5 mg each day. The efficiency of doses beyond 4.5 mg/day has actually not been set up.


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